Card 21
Question
HEPARIN SODIUM
Answer
Salicylates, some antibiotics and quinidine may increase risk of bleeding.
P125interact
Discover P125interact: 46 flashcards with questions and answers.
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- Society / Medicine
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Cards in this set
Card 22
Question
HYDROCORTISONE/METHYLPREDNISOLONE (Solu-Cortef, Solu-Medrol)
Answer
Calcium
Card 23
Question
HYDROMORPHONE (Dilaudid)
Answer
Respiratory depression, hypotension, or sedation may be potentiated by CNS depressants. Therapeutic doses of hydromorphone have caused additive CNS or respiratory depression and hypotension in Pt. taking MAO inhibitors.
Card 24
Question
KETAMINE (Ketalar)
Answer
increases the effects of opiates, barbiturates, and nondepolarizing neuromuscular blockers.
Card 25
Question
KETOROLAC (Toradol)
Answer
increase bleeding in Pt. taking anticoagulants. Effects of lithium and methotrexate may be increased.
Card 26
Question
LIDOCAINE HCL (2%)
Answer
Apnea induced with succinylcholine may be prolonged with high doses of Lidocaine. Cardiac depression may occur in conjunction with IV Dilantin. Metabolic clearance decreased in Pt. with liver disease or Pt. taking beta-blockers.
Card 27
Question
LORAZEPAM (Ativan)
Answer
May precipitate CNS depression if Pt. is already taking CNS depressant medications
Card 28
Question
MAGNESIUM SULFATE
Answer
May enhance effects of other CNS depressants. Serious changes in overall cardiac function may occur with cardiac glycosides.
Card 29
Question
MANNITOL 20%
Answer
May precipitate digitalis toxicity in when given concurrently.
Card 30
Question
MEPERIDINE (Demerol)
Answer
Do not give concurrently with MAOIs (even with a dose in the last 14 days!). Exacerbates CNS depression when given with these medications.
Card 31
Question
METOPROLOL (Lopressor)
Answer
Drugs which slow AV conduction (digoxin): effects may be additive with beta-blockers. Glucagon: Metoprolol may blunt the hyperglycemic action of glucagon. Verapamil or diltiazem may have synergistic or additive pharmacological effects when taken concurrently with beta-blockers; avoid concurrent I.V. use.
Card 32
Question
MIDAZOLAM (Versed)
Answer
Should not be used in Pt. who have taken CNS depressants
Card 33
Question
MORPHINE SULFATE
Answer
CNS depressant may potentate effects of morphine.
Card 34
Question
NITROGLYCERIN
Answer
Additive effects with other vasodilators
Card 35
Question
NOREPINEPHRINE (Levophed)
Answer
Can be deactivated by alkaline solutions. Sympathomimetic and phosphodiesterase inhibitors may exacerbate dysrhythmias.
Card 36
Question
PANCURONIUM (Pavulon)
Answer
Positive chronotropic drugs may potentiate tachycardia
Card 37
Question
PRALIDOXIME CHLORIDE (2-PAM, Protopam)
Answer
No direct drug interactions, however, Pt. with organophosphate poisoning should not be given barbiturates, morphine, theophylline, aminophylline, succinylcholine, reserpine and phenothiazines.
How Supplied: Emergency Single Dose Kit containing: One 20 ml vial of 1 gram sterile Protopam Chloride.
One 20 ml ampule of sterile diluent, disposable 20 ml syringe.
Card 38
Question
PROMETHAZINE (Phenergan)
Answer
Concomitant use of central nervous system depressants may have an additive sedative effect. Increased incidence of extrapyramidal effects occurs when given with some MAO inhibitors.Concomitant use of epinephrine may decrease blood pressure further.
Card 39
Question
RACEMIC EPINEPHRINE
Answer
Beta blockers may blunt the effect. MAOIs may potentiate the effect.
Card 40
Question
ROCURONIUM (Zemuron)
Answer
Positive chronotropic drugs may potentiate tachycardia.
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